{"id":23167,"date":"2026-09-17T11:14:28","date_gmt":"2026-09-17T11:14:28","guid":{"rendered":"https:\/\/cellgenic.com\/ll-37-benefits-handling-and-quality-standards\/"},"modified":"2026-10-21T13:04:20","modified_gmt":"2026-10-21T13:04:20","slug":"ll-37","status":"publish","type":"page","link":"https:\/\/cellgenic.com\/es\/peptidos\/ll-37\/","title":{"rendered":"LL-37: Benefits, Handling, and Quality Standards"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"23167\" class=\"elementor elementor-23167 elementor-23011\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-eed3abd e-con-full e-flex e-con e-parent\" data-id=\"eed3abd\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-98123a0 e-con-full ref-sec e-flex e-con e-parent\" data-id=\"98123a0\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-05cc51c e-flex e-con-boxed e-con e-child\" data-id=\"05cc51c\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-75c16ef e-con-full e-flex e-con e-child\" data-id=\"75c16ef\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-bed0fc6 elementor-widget elementor-widget-image\" data-id=\"bed0fc6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"683\" height=\"1024\" src=\"https:\/\/cellgenic.com\/wp-content\/uploads\/2026\/10\/ll-37-1-683x1024.jpg\" class=\"attachment-large size-large wp-image-28478\" alt=\"LL-37 Peptide\" srcset=\"https:\/\/cellgenic.com\/wp-content\/uploads\/2026\/10\/ll-37-1-683x1024.jpg 683w, https:\/\/cellgenic.com\/wp-content\/uploads\/2026\/10\/ll-37-1-200x300.jpg 200w, https:\/\/cellgenic.com\/wp-content\/uploads\/2026\/10\/ll-37-1-768x1151.jpg 768w, https:\/\/cellgenic.com\/wp-content\/uploads\/2026\/10\/ll-37-1-1025x1536.jpg 1025w, https:\/\/cellgenic.com\/wp-content\/uploads\/2026\/10\/ll-37-1-1366x2048.jpg 1366w, https:\/\/cellgenic.com\/wp-content\/uploads\/2026\/10\/ll-37-1-600x900.jpg 600w\" sizes=\"auto, (max-width: 683px) 100vw, 683px\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-60a15cc elementor-widget elementor-widget-text-editor\" data-id=\"60a15cc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Uso del producto: ESTE PRODUCTO EST\u00c1 DESTINADO \u00daNICAMENTE A SU USO COMO SUSTANCIA QU\u00cdMICA DE INVESTIGACI\u00d3N. Esta designaci\u00f3n permite el uso de sustancias qu\u00edmicas de investigaci\u00f3n estrictamente para pruebas in vitro y experimentaci\u00f3n de laboratorio. Toda la informaci\u00f3n del producto disponible en este sitio web tiene fines educativos. Est\u00e1 estrictamente prohibida por ley cualquier introducci\u00f3n de este producto en seres humanos o animales. Este producto solo debe ser manipulado por profesionales autorizados y cualificados. Este producto no es un medicamento, alimento ni cosm\u00e9tico, y no debe etiquetarse, utilizarse indebidamente ni comercializarse como medicamento, alimento o cosm\u00e9tico.     <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-42a8ea2 elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"42a8ea2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">What Is LL-37?<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-fb9668f elementor-widget elementor-widget-text-editor\" data-id=\"fb9668f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tLL-37 is the only cathelicidin-family antimicrobial peptide produced in humans, cleaved from the hCAP-18 precursor protein and originally isolated from human neutrophils. It is studied in the research literature for broad-spectrum activity against gram-positive and gram-negative bacteria as well as *Candida albicans*, making it a compound of interest in antimicrobial-resistance and innate-immunity research. \t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-aba17b2 elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"aba17b2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Beneficios y usos<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2a277bc elementor-widget elementor-widget-text-editor\" data-id=\"2a277bc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tAvailable research on LL-37 spans several areas of interest, with the standard caveat that this is a basic-research compound and not a clinical therapeutic:\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b47cc6a elementor-widget elementor-widget-text-editor\" data-id=\"b47cc6a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<ul><li><strong><strong>Antimicrobial mechanism research.<\/strong><\/strong> LL-37 is studied for its ability to disrupt bacterial lipid bilayers in a concentration-dependent manner.<\/li><li><strong><strong>Innate immunity.<\/strong><\/strong> LL-37\/hCAP-18 has been shown to be constitutively expressed in human airway epithelia, not only in neutrophil granules, broadening its research relevance beyond infection response alone.<\/li><li><strong><strong>Structural biology<\/strong>.<\/strong> Structural studies show LL-37 can oligomerize and form channel-like assemblies under membrane-mimetic conditions, an active area of biophysical research.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-09f655f elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"09f655f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">How It Works<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e9a0d13 elementor-widget elementor-widget-text-editor\" data-id=\"e9a0d13\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>LL-37&#8217;s primary studied mechanism is direct disruption of the bacterial lipid bilayer once peptide concentration crosses a threshold, driven by its amphipathic helical structure. Beyond direct membrane disruption, LL-37 is described in the literature as having pleiotropic activity \u2014 meaning research interest extends beyond antimicrobial killing alone into broader innate-immune signaling roles. <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c023263 elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"c023263\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Handling<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-fdd5554 elementor-widget elementor-widget-text-editor\" data-id=\"fdd5554\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>LL-37 should be handled according to standard peptide storage and reconstitution practices, with a reconstitution reference tool available to convert a target concentration into a working solution volume.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5eaa5c9 elementor-widget elementor-widget-text-editor\" data-id=\"5eaa5c9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><a href=\"https:\/\/cellgenic.com\/es\/calculadora-de-peptidos\/\" target=\"_blank\" rel=\"noopener\"><strong>Reconstitution Calculator \u2192<\/strong><\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9827e86 elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"9827e86\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Quality and Verification Standards<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2334433 elementor-widget elementor-widget-text-editor\" data-id=\"2334433\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Research use of LL-37 depends on independently verified identity and purity, given how sequence-sensitive antimicrobial-peptide research findings can be:<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5a3dbab elementor-widget elementor-widget-text-editor\" data-id=\"5a3dbab\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<ul><li><strong><b>Certificate of Analysis (COA)<\/b><\/strong> confirming identity and purity per lot<\/li><li><strong><b>HPLC purity data<\/b><\/strong><\/li><li><strong><b>Mycoplasma, sterility, and identity testing<\/b><\/strong> per lot<\/li><li><strong><b>cGMP-aligned manufacturing documentation<\/b><\/strong><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a0555fe elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"a0555fe\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Solicitar Acceso de Proveedor<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bc2f405 elementor-widget elementor-widget-text-editor\" data-id=\"bc2f405\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tFull pricing, ordering, and batch-specific Certificates of Analysis are available exclusively to verified providers.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-23f26f1 elementor-widget elementor-widget-text-editor\" data-id=\"23f26f1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<strong><a href=\"\/provider-verification\/register\">Apply for Provider Access \u2192<\/a><\/strong>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9ab5370 elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"9ab5370\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">References:<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-19b4cb9 elementor-widget elementor-widget-text-editor\" data-id=\"19b4cb9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<ol><li>Turner J, et al. Activities of LL-37, a Cathelin-Associated Antimicrobial Peptide of Human Neutrophils.  <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9736536\/\">PubMed \u2192<\/a><\/li><li>Henzler Wildman KA, et al. Mechanism of Lipid Bilayer Disruption by the Human Antimicrobial Peptide, LL-37.  <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12767238\/\">PubMed \u2192<\/a><\/li><li>Bals R, et al. The Peptide Antibiotic LL-37\/hCAP-18 Is Expressed in Epithelia of the Human Lung.  <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9689116\/\">PubMed \u2192<\/a><\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-873de17 e-con-full ref-sec e-flex e-con e-parent\" data-id=\"873de17\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-bcfa5b5 e-flex e-con-boxed e-con e-child\" data-id=\"bcfa5b5\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-8245387 e-con-full e-flex e-con e-child\" data-id=\"8245387\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-16e4dcb e-con-full e-flex e-con e-child\" data-id=\"16e4dcb\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ea5932b elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"ea5932b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">FAQ<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1e8fb64 elementor-widget elementor-widget-n-accordion\" data-id=\"1e8fb64\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;default_state&quot;:&quot;expanded&quot;,&quot;max_items_expended&quot;:&quot;one&quot;,&quot;n_accordion_animation_duration&quot;:{&quot;unit&quot;:&quot;ms&quot;,&quot;size&quot;:400,&quot;sizes&quot;:[]}}\" data-widget_type=\"nested-accordion.default\">\n\t\t\t\t\t\t\t<div class=\"e-n-accordion\" aria-label=\"Accordion. Open links with Enter or Space, close with Escape, and navigate with Arrow Keys\">\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-3200\" class=\"e-n-accordion-item\" open>\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"1\" tabindex=\"0\" aria-expanded=\"true\" aria-controls=\"e-n-accordion-item-3200\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> \u00bfQu\u00e9 es LL-37? <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-3200\" class=\"elementor-element elementor-element-99f15e4 e-con-full e-flex e-con e-child\" data-id=\"99f15e4\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9f99cf1 elementor-widget elementor-widget-text-editor\" data-id=\"9f99cf1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tLL-37 es un p\u00e9ptido antimicrobiano humano de la familia de las catelicidinas, derivado de la prote\u00edna precursora hCAP-18. Se estudia en investigaciones relacionadas con la actividad antimicrobiana, la inmunidad innata y las interacciones con las membranas.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-3201\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"2\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-3201\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> \u00bfPara qu\u00e9 se estudia LL-37? <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-3201\" class=\"elementor-element elementor-element-2174ae9 e-con-full e-flex e-con e-child\" data-id=\"2174ae9\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-346ef6e elementor-widget elementor-widget-text-editor\" data-id=\"346ef6e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tLa investigaci\u00f3n sobre LL-37 incluye mecanismos antimicrobianos, alteraci\u00f3n de las membranas bacterianas, se\u00f1alizaci\u00f3n de la inmunidad innata, biolog\u00eda epitelial e interacciones estructurales con las membranas lip\u00eddicas.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-3202\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"3\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-3202\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> \u00bfC\u00f3mo funciona LL-37? <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-3202\" class=\"elementor-element elementor-element-68ed2ca e-con-full e-flex e-con e-child\" data-id=\"68ed2ca\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c95404b elementor-widget elementor-widget-text-editor\" data-id=\"c95404b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tLL-37 es un p\u00e9ptido anfip\u00e1tico que puede interactuar con las membranas lip\u00eddicas bacterianas y alterarlas. La investigaci\u00f3n tambi\u00e9n examina sus funciones m\u00e1s amplias en la se\u00f1alizaci\u00f3n de la inmunidad innata y las respuestas celulares.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-3203\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"4\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-3203\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> \u00bfEs LL-37 un p\u00e9ptido antimicrobiano? <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-3203\" class=\"elementor-element elementor-element-8fc3743 e-con-full e-flex e-con e-child\" data-id=\"8fc3743\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-69a5836 elementor-widget elementor-widget-text-editor\" data-id=\"69a5836\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tS\u00ed. LL-37 es la \u00fanica catelicidina humana conocida y se ha estudiado por su actividad contra diversas bacterias Gram positivas y Gram negativas, as\u00ed como contra Candida albicans en entornos experimentales.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-3204\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"5\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-3204\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> \u00bfEst\u00e1 aprobado LL-37 para uso humano? <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-3204\" class=\"elementor-element elementor-element-fe08eb1 e-con-full e-flex e-con e-child\" data-id=\"fe08eb1\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e53b5cd elementor-widget elementor-widget-text-editor\" data-id=\"e53b5cd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tEl LL-37 de CellGenic se suministra estrictamente como sustancia qu\u00edmica de investigaci\u00f3n para experimentaci\u00f3n de laboratorio e in vitro. CellGenic no lo comercializa ni lo suministra como medicamento, tratamiento m\u00e9dico, alimento o cosm\u00e9tico.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-3205\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"6\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-3205\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> \u00bfQu\u00e9 documentaci\u00f3n de calidad debe proporcionarse para LL-37? <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-3205\" class=\"elementor-element elementor-element-2c6e7d6 e-con-full e-flex e-con e-child\" data-id=\"2c6e7d6\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-52ae804 elementor-widget elementor-widget-text-editor\" data-id=\"52ae804\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>El LL-37 de grado de investigaci\u00f3n debe contar con documentaci\u00f3n espec\u00edfica del lote, como un Certificado de An\u00e1lisis (COA), datos de pureza mediante HPLC, pruebas de identidad, pruebas de esterilidad y micoplasma cuando corresponda, y la documentaci\u00f3n de fabricaci\u00f3n pertinente.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-3206\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"7\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-3206\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> \u00bfC\u00f3mo debe manipularse LL-37 en entornos de investigaci\u00f3n? <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-3206\" class=\"elementor-element elementor-element-cc4662d e-con-full e-flex e-con e-child\" data-id=\"cc4662d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d329ead elementor-widget elementor-widget-text-editor\" data-id=\"d329ead\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tLL-37 debe manipularse de acuerdo con la ficha de especificaciones del compuesto y los protocolos de investigaci\u00f3n establecidos por el laboratorio. Los requisitos de almacenamiento y reconstituci\u00f3n pueden variar seg\u00fan la formulaci\u00f3n y la aplicaci\u00f3n experimental.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f132df5 e-flex e-con-boxed e-con e-parent\" data-id=\"f132df5\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-48c4b71 e-con-full e-flex e-con e-child\" data-id=\"48c4b71\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-1c6f511 e-con-full e-flex e-con e-child\" data-id=\"1c6f511\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-110c373 elementor-widget elementor-widget-heading\" data-id=\"110c373\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">AVISO REGULATORIO \u00b7 P\u00c9PTIDOS<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-495dabe elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"495dabe\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Estos productos est\u00e1n destinados \u00fanicamente a uso de investigaci\u00f3n de laboratorio. No son medicamentos, alimentos, cosm\u00e9ticos ni tratamientos m\u00e9dicos y no deben utilizarse para ning\u00fan tipo de administraci\u00f3n en humanos o animales. Toda la informaci\u00f3n proporcionada es \u00fanicamente para referencia educativa y cient\u00edfica, y los productos deben ser manipulados exclusivamente por profesionales autorizados y cualificados. La adulteraci\u00f3n de la marca, el uso indebido o el etiquetado incorrecto de estos productos como sustancias terap\u00e9uticas o consumibles est\u00e1 estrictamente prohibido por la ley.   <\/p><p>CellGenic ships exclusively to Mexico, Argentina, Colombia, and Per\u00fa under local license. Verified-provider-only platform from CellGenic. <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Uso del producto: ESTE PRODUCTO EST\u00c1 DESTINADO \u00daNICAMENTE A SU USO COMO SUSTANCIA QU\u00cdMICA DE INVESTIGACI\u00d3N. Esta designaci\u00f3n permite el uso de sustancias qu\u00edmicas de investigaci\u00f3n estrictamente para pruebas in vitro y experimentaci\u00f3n de laboratorio. Toda la informaci\u00f3n del producto disponible en este sitio web tiene fines educativos. Est\u00e1 estrictamente prohibida por ley cualquier introducci\u00f3n [&hellip;]<\/p>\n","protected":false},"author":174,"featured_media":0,"parent":23468,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-23167","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>LL-37: Qu\u00e9 es, Mecanismos e Investigaci\u00f3n<\/title>\n<meta name=\"description\" content=\"Conoce LL-37 y revisa la investigaci\u00f3n cient\u00edfica sobre este p\u00e9ptido, sus mecanismos moleculares y su actividad biol\u00f3gica estudiada.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cellgenic.com\/es\/peptidos\/ll-37\/\" \/>\n<meta property=\"og:locale\" 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