{"id":23459,"date":"2026-08-05T09:15:41","date_gmt":"2026-08-05T09:15:41","guid":{"rendered":"https:\/\/cellgenic.com\/kpv-benefits-handling-side-effects-and-quality-standards\/"},"modified":"2026-10-16T11:01:29","modified_gmt":"2026-10-16T11:01:29","slug":"kpv","status":"publish","type":"page","link":"https:\/\/cellgenic.com\/es\/peptidos\/kpv\/","title":{"rendered":"KPV: Benefits, Handling, Side Effects, and Quality Standards"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"23459\" class=\"elementor elementor-23459 elementor-14630\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-409168b e-con-full e-flex e-con e-parent\" data-id=\"409168b\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-fd39342 e-con-full ref-sec e-flex e-con e-parent\" data-id=\"fd39342\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-dc9553d e-flex e-con-boxed e-con e-child\" data-id=\"dc9553d\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-487af14 e-con-full e-flex e-con e-child\" data-id=\"487af14\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-fedf217 elementor-widget__width-inherit elementor-widget-tablet__width-inherit elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"fedf217\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">KPV: beneficios, manipulaci\u00f3n, efectos secundarios y est\u00e1ndares de calidad<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b8dc0dd elementor-widget elementor-widget-image\" data-id=\"b8dc0dd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"342\" src=\"https:\/\/cellgenic.com\/wp-content\/uploads\/2026\/10\/Delta-Sleep-1024x438.png\" class=\"attachment-large size-large wp-image-27010\" alt=\"Delta Sleep-Inducing Peptide\" srcset=\"https:\/\/cellgenic.com\/wp-content\/uploads\/2026\/10\/Delta-Sleep-1024x438.png 1024w, https:\/\/cellgenic.com\/wp-content\/uploads\/2026\/10\/Delta-Sleep-300x128.png 300w, https:\/\/cellgenic.com\/wp-content\/uploads\/2026\/10\/Delta-Sleep-768x328.png 768w, https:\/\/cellgenic.com\/wp-content\/uploads\/2026\/10\/Delta-Sleep-1536x657.png 1536w, https:\/\/cellgenic.com\/wp-content\/uploads\/2026\/10\/Delta-Sleep-600x257.png 600w, https:\/\/cellgenic.com\/wp-content\/uploads\/2026\/10\/Delta-Sleep.png 1918w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-12ff0ff elementor-widget elementor-widget-text-editor\" data-id=\"12ff0ff\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<strong><b>Uso del producto:<\/b><\/strong> ESTE PRODUCTO EST\u00c1 DESTINADO \u00daNICAMENTE A SU USO COMO SUSTANCIA QU\u00cdMICA DE INVESTIGACI\u00d3N. Esta designaci\u00f3n permite el uso de sustancias qu\u00edmicas de investigaci\u00f3n estrictamente para pruebas in vitro y experimentaci\u00f3n de laboratorio. Toda la informaci\u00f3n del producto disponible en este sitio web tiene fines educativos. Est\u00e1 estrictamente prohibida por ley cualquier introducci\u00f3n de este producto en seres humanos o animales. Este producto solo debe ser manipulado por profesionales autorizados y cualificados. Este producto no es un medicamento, alimento ni cosm\u00e9tico, y no debe etiquetarse, utilizarse indebidamente ni comercializarse como medicamento, alimento o cosm\u00e9tico.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4c8ec3f elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"4c8ec3f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">\u00bfQu\u00e9 es el KPV?<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-38a4a8b elementor-widget elementor-widget-text-editor\" data-id=\"38a4a8b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tEl KPV es un trip\u00e9ptido compuesto por lisina (K), prolina (P) y valina (V): los tres amino\u00e1cidos C-terminales de la hormona estimulante de los melanocitos alfa (alfa-MSH), un p\u00e9ptido natural de la hip\u00f3fisis y de los tejidos perif\u00e9ricos con actividad antiinflamatoria. El KPV conserva la se\u00f1alizaci\u00f3n antiinflamatoria asociada con su hormona de origen en una mol\u00e9cula mucho m\u00e1s peque\u00f1a, sin activar los receptores de melanocortina responsables de los efectos de pigmentaci\u00f3n y hormonales de la alfa-MSH.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ea65b65 elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"ea65b65\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Beneficios y usos<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-86ed03e elementor-widget elementor-widget-text-editor\" data-id=\"86ed03e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tLas investigaciones disponibles sobre el KPV se concentran en la se\u00f1alizaci\u00f3n antiinflamatoria y de la barrera intestinal, teniendo en cuenta que la mayor parte de los datos de apoyo procede de cultivos celulares y modelos animales en lugar de grandes ensayos en humanos:\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-813704a elementor-widget elementor-widget-text-editor\" data-id=\"813704a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<ul><li style=\"font-weight: 400;\" aria-level=\"1\"><b>Se\u00f1alizaci\u00f3n inflamatoria.<\/b><span style=\"font-weight: 400;\"> El principal hallazgo de investigaci\u00f3n; el KPV se ha estudiado por su capacidad para inhibir la activaci\u00f3n de NF-\u03baB, una v\u00eda reguladora central de la expresi\u00f3n de genes inflamatorios, en gran medida independientemente de la uni\u00f3n a los receptores de melanocortina.<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><b>Barrera intestinal e inflamaci\u00f3n intestinal.<\/b><span style=\"font-weight: 400;\"> El KPV es transportado activamente a trav\u00e9s de las membranas celulares mediante el transportador de dip\u00e9ptidos\/trip\u00e9ptidos PepT1, una propiedad estudiada por su relevancia para la captaci\u00f3n por el epitelio intestinal y la reducci\u00f3n de la se\u00f1alizaci\u00f3n inflamatoria en modelos de tejido intestinal.<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><b>Inflamaci\u00f3n cut\u00e1nea y t\u00f3pica.<\/b><span style=\"font-weight: 400;\"> Las investigaciones sobre p\u00e9ptidos relacionados con la alfa-MSH en t\u00e9rminos m\u00e1s generales han examinado la actividad antiinflamatoria en modelos de dermatitis de contacto y otras afecciones inflamatorias cut\u00e1neas.<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><b>Modulaci\u00f3n inmunitaria m\u00e1s amplia.<\/b><span style=\"font-weight: 400;\"> El KPV se estudia como parte de una familia m\u00e1s amplia de p\u00e9ptidos antiinflamatorios derivados de la alfa-MSH, junto con fragmentos relacionados que se investigan por mecanismos comparables.<\/span><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2e587b5 elementor-widget elementor-widget-text-editor\" data-id=\"2e587b5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tLa mayor parte de los datos espec\u00edficos sobre el KPV procede de investigaciones celulares y animales; los ensayos cl\u00ednicos rigurosos en humanos sobre el trip\u00e9ptido aislado son limitados, y esto debe indicarse claramente en lugar de extrapolar m\u00e1s all\u00e1 de la evidencia disponible.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f97de4b elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"f97de4b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">C\u00f3mo funciona<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-efb7b38 elementor-widget elementor-widget-text-editor\" data-id=\"efb7b38\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tEl KPV act\u00faa de forma intracelular en lugar de hacerlo exclusivamente a trav\u00e9s de un receptor de superficie. Las investigaciones indican que estabiliza I\u03baB-\u03b1, el inhibidor citoplasm\u00e1tico que mantiene inactivo NF-\u03baB, e interfiere con la translocaci\u00f3n nuclear de la subunidad p65 de NF-\u03baB, un mecanismo que interrumpe la transcripci\u00f3n de genes inflamatorios antes del punto en el que act\u00faan la mayor\u00eda de los agentes antiinflamatorios dirigidos a receptores. Este mecanismo intracelular e independiente de receptores es una de las razones por las que el KPV se ha estudiado en contextos inmunitarios intestinales, cut\u00e1neos y sist\u00e9micos, en lugar de limitarse a un \u00fanico tipo de tejido.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-59fe6d0 elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"59fe6d0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Dosis y administraci\u00f3n<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b08e8b1 elementor-widget elementor-widget-text-editor\" data-id=\"b08e8b1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p class=\"isSelectedEnd\">No existe un protocolo de dosificaci\u00f3n estandarizado para el KPV fuera de dise\u00f1os de estudios individuales, y cualquier protocolo de investigaci\u00f3n, v\u00eda o dosis es determinado exclusivamente por el investigador o profesional autorizado y su instituci\u00f3n.<\/p><p class=\"isSelectedEnd\">El transporte del KPV mediado por PepT1 lo ha convertido en objeto de investigaciones sobre la v\u00eda oral en modelos de inflamaci\u00f3n intestinal, junto con v\u00edas t\u00f3picas e inyectables estudiadas para efectos sist\u00e9micos o localizados. Esto refleja la variedad de dise\u00f1os de estudio presentes en la literatura, no una recomendaci\u00f3n para ninguna v\u00eda en particular.<\/p><p>Para los laboratorios que convierten la dosis de investigaci\u00f3n determinada por un profesional en un volumen preciso de reconstituci\u00f3n, la <a href=\"\/es\/calculadora\/\">calculadora de CellGenic<\/a> est\u00e1 abierta a cualquier visitante, sin necesidad de una cuenta.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b269348 elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"b269348\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Efectos secundarios y seguridad<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3828539 elementor-widget elementor-widget-text-editor\" data-id=\"3828539\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tEl KPV ha mostrado un perfil de tolerabilidad favorable en las investigaciones publicadas, en consonancia con su peque\u00f1o tama\u00f1o y su origen como fragmento de una hormona natural. No existen datos de seguridad humana a largo plazo para el trip\u00e9ptido aislado. Los investigadores deben establecer valores de laboratorio de referencia antes y durante cualquier protocolo.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c8d9b06 elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"c8d9b06\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Est\u00e1ndares de calidad y verificaci\u00f3n<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3f7229d elementor-widget elementor-widget-text-editor\" data-id=\"3f7229d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tCada lote de CellGenic se fabrica bajo condiciones cGMP y se somete a pruebas de micoplasma, esterilidad, identidad y potencia antes de su liberaci\u00f3n. Los Certificados de An\u00e1lisis se emiten por lote y pueden consultarse directamente utilizando el n\u00famero de lote.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-744c685 elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"744c685\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">KPV en los protocolos de CellGenic<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-79a744c elementor-widget elementor-widget-text-editor\" data-id=\"79a744c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tDentro de los propios protocolos de proveedores de CellGenic, el KPV aparece en varios paquetes de investigaci\u00f3n combinados en lugar de utilizarse como agente \u00fanico:\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4f72866 elementor-widget elementor-widget-text-editor\" data-id=\"4f72866\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<ul><li>Combinado con LL-37, <strong><a href=\"https:\/\/cellgenic.com\/es\/product\/thymosin-alpha\/\">Thymosin Alpha-1<\/a><\/strong>, BPC-157 y <strong><a href=\"\/es\/producto\/tb-500\/\">TB-500<\/a><\/strong> para investigaciones sobre biopel\u00edculas, carga de endotoxinas y recuperaci\u00f3n de heridas cr\u00f3nicas.<\/li><li>Combinado con Thymosin Alpha-1 y <strong><a href=\"https:\/\/cellgenic.com\/es\/product\/bpc-157\/\">BPC-157<\/a><\/strong> para contextos de investigaci\u00f3n relacionados con el cambio hacia TH1, la activaci\u00f3n de c\u00e9lulas T y la investigaci\u00f3n antiviral o como complemento en oncolog\u00eda.<\/li><li>Combinado con Thymosin Alpha-1 y BPC-157 para apoyar la investigaci\u00f3n sobre neuroinflamaci\u00f3n y dolor neurop\u00e1tico.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b6d34cc elementor-widget elementor-widget-text-editor\" data-id=\"b6d34cc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tLos proveedores que desarrollen un protocolo centrado en el sistema inmunitario o la inflamaci\u00f3n pueden revisar directamente las combinaciones completas y sus productos componentes.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d645767 elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"d645767\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Convi\u00e9rtete en un proveedor verificado<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a6a1894 elementor-widget elementor-widget-text-editor\" data-id=\"a6a1894\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tLos Certificados de An\u00e1lisis, la documentaci\u00f3n de los lotes y los precios est\u00e1n disponibles exclusivamente para m\u00e9dicos, operadores de cl\u00ednicas e investigadores verificados.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bd408f0 elementor-widget elementor-widget-text-editor\" data-id=\"bd408f0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<strong><a href=\"https:\/\/cellgenic.com\/es\/registro\/\">Convertirse en proveedor \u2192<\/a><\/strong>Un especialista de CellGenic se pondr\u00e1 en contacto en el plazo de un d\u00eda h\u00e1bil. Una vez verificada la cuenta, los precios completos y los Certificados de An\u00e1lisis se desbloquean autom\u00e1ticamente.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-409dbfe elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"409dbfe\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Referencias:<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3aef217 elementor-widget elementor-widget-text-editor\" data-id=\"3aef217\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<ol><li><a class=\"text-secondary underline decoration-1 underline-offset-2 hover:no-underline focus-visible:outline-none focus-visible:ring-[3px] focus-visible:ring-ring\/50\" href=\"https:\/\/www.fda.gov\/media\/193346\/download\" target=\"_blank\" rel=\"noopener noreferrer\">FDA 2026 evidence and safety review of KPV-related substances<\/a><\/li><li><a class=\"text-secondary underline decoration-1 underline-offset-2 hover:no-underline focus-visible:outline-none focus-visible:ring-[3px] focus-visible:ring-ring\/50\" href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC2431115\/\" target=\"_blank\" rel=\"noopener noreferrer\">Dalmasso et al.: KPV cell and mouse colitis study<\/a><\/li><li><a class=\"text-secondary underline decoration-1 underline-offset-2 hover:no-underline focus-visible:outline-none focus-visible:ring-[3px] focus-visible:ring-ring\/50\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40073467\/\" target=\"_blank\" rel=\"noopener noreferrer\">KPV keratinocyte and three-dimensional skin model study<\/a><\/li><li><a class=\"text-secondary underline decoration-1 underline-offset-2 hover:no-underline focus-visible:outline-none focus-visible:ring-[3px] focus-visible:ring-ring\/50\" href=\"https:\/\/www.fda.gov\/advisory-committees\/advisory-committee-calendar\/july-23-24-2026-meeting-pharmacy-compounding-advisory-committee-07232026\" target=\"_blank\" rel=\"noopener noreferrer\">FDA July 2026 Pharmacy Compounding Advisory Committee materials<\/a><\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c182b74 e-con-full ref-sec e-flex e-con e-parent\" data-id=\"c182b74\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-4af805c e-flex e-con-boxed e-con e-child\" data-id=\"4af805c\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-ead2d6c e-con-full e-flex e-con e-child\" data-id=\"ead2d6c\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-06ebe56 e-con-full e-flex e-con e-child\" data-id=\"06ebe56\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b9a883c elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"b9a883c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">FAQ<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-88cbb71 elementor-widget elementor-widget-n-accordion\" data-id=\"88cbb71\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;default_state&quot;:&quot;expanded&quot;,&quot;max_items_expended&quot;:&quot;one&quot;,&quot;n_accordion_animation_duration&quot;:{&quot;unit&quot;:&quot;ms&quot;,&quot;size&quot;:400,&quot;sizes&quot;:[]}}\" data-widget_type=\"nested-accordion.default\">\n\t\t\t\t\t\t\t<div class=\"e-n-accordion\" aria-label=\"Accordion. Open links with Enter or Space, close with Escape, and navigate with Arrow Keys\">\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-1430\" class=\"e-n-accordion-item\" open>\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"1\" tabindex=\"0\" aria-expanded=\"true\" aria-controls=\"e-n-accordion-item-1430\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> \u00bfQu\u00e9 es KPV? <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-1430\" class=\"elementor-element elementor-element-eab33e8 e-con-full e-flex e-con e-child\" data-id=\"eab33e8\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e9d5dab elementor-widget elementor-widget-text-editor\" data-id=\"e9d5dab\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tKPV es un trip\u00e9ptido compuesto por tres amino\u00e1cidos: lisina, prolina y valina. Se deriva de la hormona estimulante de los melanocitos alfa (\u03b1-MSH) y se estudia por sus posibles propiedades antiinflamatorias.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-1431\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"2\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-1431\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> \u00bfCu\u00e1les son los posibles beneficios de KPV? <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-1431\" class=\"elementor-element elementor-element-4a7b654 e-con-full e-flex e-con e-child\" data-id=\"4a7b654\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-fede4cf elementor-widget elementor-widget-text-editor\" data-id=\"fede4cf\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tKPV se est\u00e1 investigando por su posible papel en la regulaci\u00f3n de las se\u00f1ales inflamatorias, la inflamaci\u00f3n intestinal, la funci\u00f3n de la barrera intestinal y la inflamaci\u00f3n de la piel. La mayor parte de la evidencia disponible procede de estudios de laboratorio y de investigaciones en animales.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-1432\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"3\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-1432\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> \u00bfC\u00f3mo funciona KPV? <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-1432\" class=\"elementor-element elementor-element-0bac9f9 e-con-full e-flex e-con e-child\" data-id=\"0bac9f9\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-71ffc78 elementor-widget elementor-widget-text-editor\" data-id=\"71ffc78\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tLas investigaciones sugieren que KPV podr\u00eda ayudar a regular la v\u00eda de se\u00f1alizaci\u00f3n NF-\u03baB, que desempe\u00f1a un papel importante en la respuesta inflamatoria del organismo.\n\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-1433\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"4\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-1433\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> \u00bfExisten protocolos de dosificaci\u00f3n de KPV establecidos para la investigaci\u00f3n? <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-1433\" class=\"elementor-element elementor-element-b0e88bf e-con-full e-flex e-con e-child\" data-id=\"b0e88bf\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-fadfe0b elementor-widget elementor-widget-text-editor\" data-id=\"fadfe0b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tActualmente, no existe un protocolo de dosificaci\u00f3n estandarizado y validado cl\u00ednicamente para KPV. Los protocolos de investigaci\u00f3n var\u00edan seg\u00fan el dise\u00f1o del estudio y el modelo experimental utilizado.\n\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-1434\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"5\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-1434\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> \u00bfCu\u00e1l es el perfil de seguridad de KPV? <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-1434\" class=\"elementor-element elementor-element-3d913bb e-con-full e-flex e-con e-child\" data-id=\"3d913bb\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-63ecbd1 elementor-widget elementor-widget-text-editor\" data-id=\"63ecbd1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tLos datos sobre la seguridad del KPV aislado en seres humanos son limitados, y sus efectos a largo plazo a\u00fan no est\u00e1n bien establecidos. Los resultados de las investigaciones no deben interpretarse como una prueba de que su uso en humanos sea seguro.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-54deb28 e-flex e-con-boxed e-con e-parent\" data-id=\"54deb28\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-c5cc7bb e-con-full e-flex e-con e-child\" data-id=\"c5cc7bb\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-b8bb725 e-con-full e-flex e-con e-child\" data-id=\"b8bb725\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c830e40 elementor-widget elementor-widget-heading\" data-id=\"c830e40\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">AVISO REGULATORIO \u00b7 P\u00c9PTIDOS<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-74aaa5c elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"74aaa5c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">Estos productos est\u00e1n destinados exclusivamente a la investigaci\u00f3n en laboratorio. No son medicamentos, alimentos, cosm\u00e9ticos ni tratamientos m\u00e9dicos, y no deben utilizarse para su administraci\u00f3n a personas ni animales bajo ning\u00fan concepto. Toda la informaci\u00f3n que te damos es solo con fines educativos y de referencia cient\u00edfica, y los productos solo deben ser manipulados por profesionales cualificados y con la licencia correspondiente. La ley proh\u00edbe estrictamente el etiquetado enga\u00f1oso, el uso indebido o la clasificaci\u00f3n err\u00f3nea de estos productos como sustancias terap\u00e9uticas o de consumo.   <\/span><\/p><p><span style=\"font-weight: 400;\">CellGenic ships exclusively to Mexico, Argentina, Colombia, and Per\u00fa under local license. Verified-provider-only platform from CellGenic. <\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>KPV: beneficios, manipulaci\u00f3n, efectos secundarios y est\u00e1ndares de calidad Uso del producto: ESTE PRODUCTO EST\u00c1 DESTINADO \u00daNICAMENTE A SU USO COMO SUSTANCIA QU\u00cdMICA DE INVESTIGACI\u00d3N. Esta designaci\u00f3n permite el uso de sustancias qu\u00edmicas de investigaci\u00f3n estrictamente para pruebas in vitro y experimentaci\u00f3n de laboratorio. Toda la informaci\u00f3n del producto disponible en este sitio web tiene [&hellip;]<\/p>\n","protected":false},"author":174,"featured_media":0,"parent":23468,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-23459","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>KPV: Qu\u00e9 es, Mecanismos e Investigaci\u00f3n<\/title>\n<meta name=\"description\" content=\"Conoce KPV y revisa la investigaci\u00f3n cient\u00edfica sobre sus mecanismos moleculares, propiedades estudiadas y posibles aplicaciones experimentales.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cellgenic.com\/es\/peptidos\/kpv\/\" \/>\n<meta property=\"og:locale\" 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