{"id":2015,"date":"2023-08-23T14:18:07","date_gmt":"2023-08-23T14:18:07","guid":{"rendered":"https:\/\/cellgenic.com\/product\/exosomas-liofilizados-cellgenic-ortopedia\/"},"modified":"2026-01-06T20:32:56","modified_gmt":"2026-01-06T20:32:56","slug":"exosomas-liofilizados-cellgenic-ortopedia","status":"publish","type":"product","link":"https:\/\/cellgenic.com\/es\/product\/exosomas-liofilizados-cellgenic-ortopedia\/","title":{"rendered":"Exosomas liofilizados Cellgenic Ortopedia"},"content":{"rendered":"<p style=\"text-align: center;\">Los exosomas son ves\u00edculas de tama\u00f1o nanom\u00e9trico (30-200 nm) liberadas constantemente por casi todas las c\u00e9lulas. La capacidad de los exosomas para viajar entre las c\u00e9lulas y entregar su carga, que incluye l\u00edpidos, prote\u00ednas y \u00e1cidos nucleicos, los convierte en una atractiva opci\u00f3n de terapia sin c\u00e9lulas para tratar m\u00faltiples enfermedades. Aqu\u00ed investigamos por primera vez si los exosomas derivados de c\u00e9lulas madre mesenquimales derivadas de tejido adiposo humano pueden mejorar la dermatitis at\u00f3pica (DA) en un modelo de rat\u00f3n in vivo. Cuando se inyectaron por v\u00eda intravenosa (IV) o subcut\u00e1nea (SC) en ratones NC\/Nga tratados con ant\u00edgenos de \u00e1caros del polvo dom\u00e9stico, se observ\u00f3 que los exosomas de ERC reduc\u00edan los s\u00edntomas patol\u00f3gicos, como la puntuaci\u00f3n cl\u00ednica, los niveles de IgE s\u00e9rica, el n\u00famero de eosin\u00f3filos en sangre y la infiltraci\u00f3n de mastocitos, c\u00e9lulas CD86+ y CD206+ en las lesiones cut\u00e1neas. Los exosomas de ERC tambi\u00e9n redujeron significativamente la expresi\u00f3n de ARNm de diversas citocinas inflamatorias, como la interleucina (IL)-4, la IL-23, la IL-31 y el factor de necrosis tumoral (TNF-) en las lesiones cut\u00e1neas de EA del hielo Nc\/Nga. En conjunto, estos resultados sugieren que los ERC-exosomas pueden ser una nueva y prometedora modalidad terap\u00e9utica sin c\u00e9lulas para el tratamiento de la EA. (Byoung Seung Cho, Jin Ock Kin, Dae Hyun Ha y Young Weon &#8211; Terapia de investigaci\u00f3n con c\u00e9lulas madre)<\/p>\n","protected":false},"excerpt":{"rendered":"<p>(Caja de 5 viales + 5 diluyentes)<\/p>\n","protected":false},"featured_media":1881,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_joinchat":[]},"product_brand":[],"product_cat":[186,170],"product_tag":[],"class_list":{"0":"post-2015","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-exosomas","7":"product_cat-productos-celulares","9":"first","10":"instock","11":"shipping-taxable","12":"product-type-simple","13":"add-to-wishlist-before_image"},"group_of_quantity":0,"min_quantity":5,"max_quantity":"","exclude_order_quantity_value_rules":"no","exclude_category_quantity_rules":"no","combine_variations":"no","acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Exosomas liofilizados Cellgenic Ortopedia - Cellgenic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cellgenic.com\/?post_type=product&p=437\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Exosomas liofilizados Cellgenic Ortopedia - Cellgenic\" \/>\n<meta property=\"og:description\" content=\"(Caja de 5 viales + 5 diluyentes)\" \/>\n<meta property=\"og:url\" content=\"https:\/\/cellgenic.com\/?post_type=product&amp;p=437\" \/>\n<meta property=\"og:site_name\" content=\"Cellgenic\" \/>\n<meta property=\"article:modified_time\" content=\"2026-01-06T20:32:56+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/cellgenic.com\/wp-content\/uploads\/2023\/08\/Cellgenic-Lyophilized-Exosomes-Orthopedics-1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1736\" \/>\n\t<meta property=\"og:image:height\" content=\"2278\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minuto\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/cellgenic.com\\\/?post_type=product&p=437\",\"url\":\"https:\\\/\\\/cellgenic.com\\\/?post_type=product&p=437\",\"name\":\"Exosomas liofilizados Cellgenic Ortopedia - Cellgenic\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/cellgenic.com\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/cellgenic.com\\\/?post_type=product&p=437#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/cellgenic.com\\\/?post_type=product&p=437#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/cellgenic.com\\\/wp-content\\\/uploads\\\/2023\\\/08\\\/Cellgenic-Lyophilized-Exosomes-Orthopedics-1.jpg\",\"datePublished\":\"2023-08-23T14:18:07+00:00\",\"dateModified\":\"2026-01-06T20:32:56+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/cellgenic.com\\\/?post_type=product&p=437#breadcrumb\"},\"inLanguage\":\"es\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/cellgenic.com\\\/?post_type=product&p=437\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\\\/\\\/cellgenic.com\\\/?post_type=product&p=437#primaryimage\",\"url\":\"https:\\\/\\\/cellgenic.com\\\/wp-content\\\/uploads\\\/2023\\\/08\\\/Cellgenic-Lyophilized-Exosomes-Orthopedics-1.jpg\",\"contentUrl\":\"https:\\\/\\\/cellgenic.com\\\/wp-content\\\/uploads\\\/2023\\\/08\\\/Cellgenic-Lyophilized-Exosomes-Orthopedics-1.jpg\",\"width\":1736,\"height\":2278,\"caption\":\"Lyophilized Exosomes orthopedics\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/cellgenic.com\\\/?post_type=product&p=437#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/cellgenic.com\\\/inicio\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Tienda\",\"item\":\"https:\\\/\\\/cellgenic.com\\\/tienda\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Exosomas liofilizados Cellgenic Ortopedia\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/cellgenic.com\\\/#website\",\"url\":\"https:\\\/\\\/cellgenic.com\\\/\",\"name\":\"Cellgenic\",\"description\":\"Explore Cellgenic&#039;s advanced regenerative medicine products, specializing in high-quality exosomes for therapeutic applications. 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