Price: $650

100% Natural. No animal products. GMO Free.
Purified Cord Blood MSC Exosomes in saline.

Cellgenic Exosomes is a purified xeno-free, chemically defined, cell-free cord blood MSC derived exosome re-suspended in 0.9% normal saline.Contains over 5 billion purified MSC exosomes per vial.

Product description:

Since few transplanted cells persist in vivo, the beneficial effects of cell therapy may lie in the secreted factors being the active component of this treatment.

A key part of paracrine secretion is Exosomes, which are membrane vesicles that are stored intracellularly in endosomal compartments and are secreted when these structures fuse with the cell plasma membrane.

  • Exosomes contain protein, DNA, and RNA, thus making them an attractive vector of paracrine signals delivered by stem cells.
  • Exosomes may also be "loaded" with predetermined proteins and nucleic acid to achieve a desired effect (1).
  • Exosomes can be stored as an "off-the-shelf" product having the potential for circumventing many of the limitations of\viable cells for therapeutic applications in regenerative medicine.
  • In vitro, exosomes from pre-adipocytes stimulate cell proliferation in a wound healing model.
  • In vivo, adipose-graft derived exosomes have been shown to be a promising tool for skin repair and remodeling (2)

Components of Cellgenic Exosomes

Exosomes, Cytokines, Chemokines, Growth Factors, Hyaluronic Acid (HA)

Exosomes can Deliver these signals

Anti-Apoptotic, Anti-Fibrotic, Pro-Angiogenic, Pro-Differentiation, Pro-Proliferation, Immunomodulatory, Immune Privileged

Maximum Safety and Quality Control

Sterile-filtered without radiation, No cryoprotectant or dilutants ever used Endotoxin and USP <71> testing on all lots. Non Expanded/Non Cultured 100% pure liquid allogeneic secretion. Maximum bioavailability. Non-nucleated cell Minimal Manipulated

Quality Compliance & Donor Screening

Cellgenic Exosomes is procured and processed in the United States according to standards and regulations established by the American Association of Tissue Banks (AATB), the United States Food & Drug Administration (FDA). All local donors. Donor ethics and non-reactive FDA approved serological screening includes:

Donor Consent Prior
to Collections

  • HCV (Hepatitis C Antibody) 
  • HBsAG (Hepatitis B Surface Antigen) 
  • HIV 1/11-Ab (HIV Nucleic Acid Test) 
  • HBcAb (Hepatitis B core Antibody) 
  • HCV NAt (HCV Nucleic Acid Test)

RECEIVING CELLGENIC EXOSOMES

  • DRY ICE

    Cellgenic Flox Exosomes is a human tissue allograft that is received in a box on dry ice.
  • CHECK LABEL

    Before opening the box, check the label.
  • EXPIRY DATE

    You must use graft before the expiry date or transfer to a freezer.
  • STORE

    Move to a Freezer and store at -20C or lower.

Preparation and Dilution

The necessary materials for the procedure are:

  • Cellgenic Exosomes Vials
  • 3cc Syringe
  • 18 Gauge Needle
  • 22 to 27 Gauge Needle
  • The Dilutant of choice

Aceptable Dilutants:

  • Normal saline
  • 1% preservative free pain lidocaine
  • Platelet Rich Plasma

Prohibited Dilutants:

  • Glycerol
  • Glucose Solutions (eg.D5NS)
  • Epinephrine
  • Lidocaine/marcaine with preservatives
  • Lidocaine/Marcaine in Joints
  • Chemical Debridement (eg. Santyl)

PREPARATION & MIXING

STEP BY STEP PROCEDURE

  • Removed the package from freezer. Cut the Package.
  • Defrost vial by holding still in hand for 3-5 minutes.
    (Do not shake the vial)
  • Fill syringe with dilutant. (Typically 1:1 ratio)
  • Draw Cellgenic Exosomes into syringe with 18G Needle.
  • Use a 22 to 27G needle for implantation.

POST IMPLANTATION PROTOCOL

Stimulation of inflammation of tissue is desired to increase success:

  • No Anti Inflammatories
  • No Aspirin
  • Minimize Immobilization (joints)
  • No Icing
  • Protected Active rehabilitation is recommended.

Address:

Global Stem Cells Group Inc
14750 NW 77TH Court
Suite 304, Miami Lakes, Florida, 33016, United States.

© 2019. All rights reserved.
A Global Stem Cells Group Company.

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