This product is intended for use by medical professionals only. If you are an active licensed physician and wish to place an order please contact our team to create an account before placing an order.
YOUR ORDER WILL NOT BE SHIPPED WITHOUT PRIOR ACCOUNT ACTIVATION AND VERIFICATION.
Mechanism of Action
In placental therapy, extracts of placenta containing polydeoxyribonucleotide (PDRN), enzymes, nucleic acids, amino acids, peptides, vitamins, trace elements, minerals and growth factors are normally administered via intramuscular injection. Administered placental extracts are readily absorbed by binding to specific receptors present on the surface of targeted cells followed by stimulating inactive or damaged cells, tissues and organs in the body, thus providing tissue repair and regeneration. In addition, placental extracts also exhibit many other therapeutic properties and act as a stimulant for tissue repair, wound healing, immunomodulation, anti-inflammatory, cellular proliferation and tissue regeneration.
Properties of Human Placenta
The placenta serves as a connection between the mother and fetus and delivers nutrients including glucose, amino acids, fatty acids, vitamins and minerals for fetal growth and development. These nutrients can also be retained after delivery. Placental extracts contain various components such as collagen, elastin, laminin, nucleic acids, amino acids, peptides, cytokines and growth factors. Previous research has investigated and documented the nutrient content and properties of placenta.
NUCLEIC ACIDS: Placenta contains ribonucleic acid (RNA) and deoxyribonucleic acid (DNA) which can activate the biosynthesis of nucleic acids. An active component extracted from placenta, Polydeoxyribonucleotide (PDRN), can help in wound healing and treatment of ulcers, wounds, and scars. Stellar Biomolecular Research and Stellar Biomolecular Innovations have developed a cold-enzymatic processing method to manufacture liquid forms of placental extracts, which are widely used across 75 countries for various medical conditions. These extracts possess high bioavailability due to their low molecular weight and linear size of the peptides.
AMINO ACIDS AND PEPTIDES: Amino acids are important nutrients during intrauterine life, and the placenta contains both essential and non-essential amino acids which can stimulate fibroblast and collagen production and reduce skin pigmentation. Stellar Biomolecular Innovations has incorporated placental peptides into its skin rejuvenation formula, SPMCE, which has both aesthetic and therapeutic benefits for hypertrophic and keloid scars.
VITAMINS, MINERALS AND TRACE ELEMENTS: Vitamins, minerals, and trace elements are crucial for the health and development of organs. The placenta contains vitamin B binding sites and extracts of placenta contain various vitamins such as B1, B2, B5, B6, B7, B9, and B12 which are important for cell metabolism, division, development, and energy production. Encapsulated placental extracts also contain minerals and trace elements including calcium, copper, iron, magnesium, manganese, phosphorus, potassium, silicon, sodium, and zinc which are essential for normal human development and functioning.
EXTRACELLULAR MATRIX COMPONENTS: The extracellular matrix (ECM) in the dermal layer is composed of collagens, proteoglycans/glycosaminoglycans, elastin, fibronectin, laminins and other glycoproteins. The human placenta contains collagens (type I, III, IV, V, VII, VIII and XVI, XVII), elastin, fibronectin and laminin. These components provide structural integrity, tensile strength, elasticity, cell adhesion regulation, tissue development, cellular migration and chemotaxis to surrounding cells.
CYTOKINES AND GROWTH FACTORS: Placental extracts contain cytokines and growth factors that act as messengers and stimulate cellular response through autocrine, paracrine, and endocrine signaling. These growth factors regulate growth, proliferation, migration, and differentiation of cells. Placental extracts contain G-CSF, GM-CSF, EGF, FGF, HGF, IGF, PDGF, TGF, VEGF which have various physiological effects including immunomodulation, anti inflammatory, wound healing, cellular proliferation and regeneration.
Human Placenta Therapy is used to treat a variety of conditions, including musculoskeletal injuries, skin aging, and chronic pain. It is also an excellent tool to promote post-operative healing, improve immune function, and treat hormonal imbalances.
- Wound healing: It contains a variety of growth factors, cytokines, and ECM proteins that promote wound healing and tissue repair. Studies have shown that Human Placenta Therapy is effective in accelerating the healing of chronic wounds such as diabetic foot ulcers and venous leg ulcers.
- Skin rejuvenation: The growth factors and ECM proteins found in human placenta have anti-aging effects and promote skin rejuvenation. It is used as a treatment for wrinkles, fine lines, and other signs of skin aging.
- Sports injuries: It is used as a treatment for sports injuries such as muscle strains and ligament sprains. The growth factors and cytokines found in human placenta help reduce inflammation and promote tissue repair.
- Orthopedic conditions: It is used as a treatment for orthopedic conditions such as osteoarthritis and cartilage damage. The growth factors and ECM proteins found in human placenta promote cartilage repair and reduce inflammation.
- Neurological conditions: It is used as a treatment for neurological conditions such as stroke and traumatic brain injury. The growth factors and cytokines found in human placenta can promote neuro-regeneration and reduce inflammation in the brain.
- Musculoskeletal injuries: It is used as a treatment for musculoskeletal injuries such as tendonitis and sprains due to its ability to reduce inflammation and promote tissue repair.
- Chronic pain: It is used as a treatment for chronic pain conditions such as fibromyalgia and neuropathic pain due to its ability to reduce inflammation and promote tissue repair.
- To promote post-operative healing: It is used as a treatment to promote post-operative healing and reduce the risk of infection and other complications.
- Improve immune function: It is used as a treatment to improve immune function and reduce the risk of infections and other immune-related conditions.
- Treat hormonal imbalances: It is used as a treatment for hormonal imbalances such as menopause and polycystic ovary syndrome (PCOS) due to its ability to regulate hormone levels and promote tissue repair.