This product is intended for use by medical professionals only. If you are an active licensed physician and wish to place an order please contact our team to create an account before placing an order.
YOUR ORDER WILL NOT BE SHIPPED WITHOUT PRIOR ACCOUNT ACTIVATION AND VERIFICATION.
Mechanism of Action
In placental therapy, extracts of placenta containing polydeoxyribonucleotide (PDRN), enzymes, nucleic acids, amino acids, peptides, vitamins, trace elements, minerals and growth factors are normally administered via intramuscular injection. Administered placental extracts are readily absorbed by binding to specific receptors present on the surface of targeted cells followed by stimulating inactive or damaged cells, tissues and organs in the body, thus providing tissue repair and regeneration. In addition, placental extracts also exhibit many other therapeutic properties and act as a stimulant for tissue repair, wound healing, immunomodulation, anti-inflammatory, cellular proliferation and tissue regeneration.
Properties of Human Placenta
The placenta serves as a connection between the mother and fetus and delivers nutrients including glucose, amino acids, fatty acids, vitamins and minerals for fetal growth and development. These nutrients can also be retained after delivery. Placental extracts contain various components such as collagen, elastin, laminin, nucleic acids, amino acids, peptides, cytokines and growth factors. Previous research has investigated and documented the nutrient content and properties of placenta.
NUCLEIC ACIDS: Placenta contains ribonucleic acid (RNA) and deoxyribonucleic acid (DNA) which can activate the biosynthesis of nucleic acids. An active component extracted from placenta, Polydeoxyribonucleotide (PDRN), can help in wound healing and treatment of ulcers, wounds, and scars. Stellar Biomolecular Research and Stellar Biomolecular Innovations have developed a cold-enzymatic processing method to manufacture liquid forms of placental extracts, which are widely used across 75 countries for various medical conditions. These extracts possess high bioavailability due to their low molecular weight and linear size of the peptides.
AMINO ACIDS AND PEPTIDES: Amino acids are important nutrients during intrauterine life, and the placenta contains both essential and non-essential amino acids which can stimulate fibroblast and collagen production and reduce skin pigmentation. Stellar Biomolecular Innovations has incorporated placental peptides into its skin rejuvenation formula, SPMCE, which has both aesthetic and therapeutic benefits for hypertrophic and keloid scars.
VITAMINS, MINERALS AND TRACE ELEMENTS: Vitamins, minerals, and trace elements are crucial for the health and development of organs. The placenta contains vitamin B binding sites and extracts of placenta contain various vitamins such as B1, B2, B5, B6, B7, B9, and B12 which are important for cell metabolism, division, development, and energy production. Encapsulated placental extracts also contain minerals and trace elements including calcium, copper, iron, magnesium, manganese, phosphorus, potassium, silicon, sodium, and zinc which are essential for normal human development and functioning.
EXTRACELLULAR MATRIX COMPONENTS: The extracellular matrix (ECM) in the dermal layer is composed of collagens, proteoglycans/glycosaminoglycans, elastin, fibronectin, laminins and other glycoproteins. The human placenta contains collagens (type I, III, IV, V, VII, VIII and XVI, XVII), elastin, fibronectin and laminin. These components provide structural integrity, tensile strength, elasticity, cell adhesion regulation, tissue development, cellular migration and chemotaxis to surrounding cells.
CYTOKINES AND GROWTH FACTORS: Placental extracts contain cytokines and growth factors that act as messengers and stimulate cellular response through autocrine, paracrine, and endocrine signaling. These growth factors regulate growth, proliferation, migration, and differentiation of cells. Placental extracts contain G-CSF, GM-CSF, EGF, FGF, HGF, IGF, PDGF, TGF, VEGF which have various physiological effects including immunomodulation, anti inflammatory, wound healing, cellular proliferation and regeneration.
Safety and Efficacy
Human Placenta Therapy has been used for decades in some cultures, particularly in traditional medicine practices.
Administering Human placental extract directly to a wound margin promotes wound healing
Human placental extract activates a wide array of gene expressions related to skin functions.
Human placental extract systematically helps collagenesis leading to potent healing of wounds
Human placental extract used to treat fatigue, postmenopausal symptoms, wound healing, and growth retardation in Korea.
Placenta Extracts have been utilized in a variety of clinical indications, including wound healing where the growth factors, amino acids, and angiogenic-promoting agents have proven to be beneficial.
Get it Touch!
