Post-GLP-1 Regenerative Medicine: Beyond Weight

Physiology and mechanisms of action. GLP-1 agonists, dual agonists and new molecules under investigation. Pharmacological and clinical differences. Indications, contraindications, precautions and patient selection.

Clinical history, body composition and functional assessment. Nutritional status, metabolic health, hormonal context and emotional well-being. Complementary studies according to risk. Nutrition, strength, sleep and correction of deficiencies. Baseline facial, body and hair records.

Initiation, titration and maintenance by molecule. Tolerability and management of adverse effects. Distinguishing weight plateau, lack of response and possible tachyphylaxis according to the effect assessed. Adherence, administration technique and secondary causes. Criteria for switching between molecules and mechanisms: transition, follow-up and the absence of direct dose equivalence.

20 minutes.

Facial: loss of volume, support and skin quality. Body: laxity, deflation and excess skin. Hair: telogen effluvium, androgenetic alopecia and differential diagnoses. Muscle: loss of lean mass, weakness and sarcopenia. Well-being: fatigue, anhedonia and adaptation to the new body image. Assessment algorithms and referral criteria.

Clinical nutrition, exercise and orthomolecular medicine oriented to needs and deficiencies. GH, analogues and secretagogues: specific indications, risks and evidence in this context. GHK-Cu and other peptides. PRP, platelet derivatives, autologous fibroblasts and exosomes/extracellular vesicles. Integration with aesthetic technologies and treatments. Sequencing by tissue, clinical timing and objectives; evidence, limits and regulatory status.

Case assessment: history, weight trajectory, photographs and tissue-by-tissue examination. Identification of the predominant problem. Reasoned selection of tools and demonstration of a technique appropriate to the indication and available resources. Follow-up plan and outcome measurement.

Answering questions on titration, treatment changes, combinations, complications and procedure selection. Integrating the approach before, during and after weight loss.