Exosomes are nano-sized vesicles (30-200 nm) constrantly released by almost all cells. The ability of exosomes to travel between cells and deliver their cargo, which includes lipids, proteins, and nucleic acids, makes them an appealing cell-free therapy option to treat multiple diseases. Here, we investigated for the first time whether human adipose tissue-derived mesenchymal stem cell-derived exosomes can ameliorate atopic dermatitis (AD) in an in vivo mouse model. When injected either intravenously (IV) or subcutaneously (SC) into NC/Nga mice treated with house dust mite antigens, ERC-exosomes were found to reduce pathological symptoms such as clinical score, the levels of serum IgE, the number of eosinophils in blood, and the infultration of mast cells, CD86+, and CD206+ cells in skin lesions. ERC-exosomes also significantly reduced mRNA expression of various inflammatory cytokines such as interleukin (IL)-4, IL-23, IL-31, and tumor necrosis factor (TNF-) in AD skin lesions of Nc/Nga ice. Taken together, these results suggest that ERC-exosomes can be a novel promising cell-free therapeutic modality for AD treatment. (Byoung Seung Cho, Jin Ock Kin, Dae Hyun Ha and Young Weon – Stem Cell Research Therapy)
Lot-traced · COA on file · Sterility & mycoplasma tested
PEPTIDE DOSE: Select dose
DRAW SYRINGE TO: Select values
YOUR VIAL CONTAINS: Select values
CONCENTRATION: Select values
Cellgenic Lyophilized Exosomes for Aesthetics combines advanced exosome technology with growth factors, peptides, amino acids, vitamins, minerals, and coenzymes to support skin rejuvenation and tissue regeneration.
Each box contains 3 vials of lyophilized exosomes formulated to deliver potent cellular signaling molecules involved in skin repair and renewal. Exosomes are naturally occurring extracellular vesicles responsible for cell-to-cell communication, helping transfer proteins, RNA, growth factors, and other bioactive components between cells.
Apply once, get reviewed by our team, and access provider-only pricing across peptides, exosomes, and cellular products.
PRODUCT USAGE: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. This product is intended strictly for laboratory research and qualifies under appropriate regulatory frameworks for research-only use. It is not intended to diagnose, treat, cure, or prevent any disease or condition. This product should only be handled by licensed, qualified professionals. It is not intended for use by the general public. Bodily introduction of any kind into humans or animals is strictly forbidden by law.
